Cuno Biocap Zeta Plus Za Series Filter Bce03a120za05a

US $88.88

  • Greensboro, North Carolina, United States
  • Jan 30th
CUNO BioCap Zeta Plus ZA Series Filter BCE03A120ZA05A Note: Pictures 5 to 11 are not from the filter on sale and for illustration only.  The box is intact and not opened. Catalogue Number Number of Cells Packaging  Grade BCE 03 = 3-cell A = Single Filter 120ZA05A  Catalog No.: BCE03A120ZA05A The Zeta Plus EXT ZA Series filter extends depth filtration capacity and extends protection of downstream membranes thereby extending filter life and lowering overall filtration costs. Zeta Plus EXT ZA Series is a family of advanced dual zone depth filters designed to provide optimal clarification of bioprocess, biological and pharmaceutical fluids. Zeta Plus EXT ZA Series filters consist of two distinct layers or “zones” of filter media with the upstream zone more open than the downstream zone. This structure enhances the contaminant holding capacity of the filter media, since larger particles are trapped in the upper zone of the filter media and smaller particles are trapped in the lower zone, reducing premature plugging and extending service life. The two filter “zones” can be independently selected and combined to optimise performance. Applications Zeta Plus EXT ZA Series filters are optimised for clarification of mammalian cell harvest fluids and for optimal protection of downstream sterilsing grade membrane filters. In addition, their strong positive charge provides enhanced removal of negatively charged contaminants. In solution, cells and cellular debris, endotoxins and contaminating nucleic acids (DNA, RNA) carry a negative charge. 3M Purification’s application of positive zeta potential to ZA filter media creates a filter matrix that enhances the capture of negatively charged contaminants for maximum filtration performance. The strong positive charge over a broad pH range makes these filters ideal for cell broth clarification and for protection of downstream membrane filters. •Clarification of mammalian cell culture process fluids (cell separation) •Protection of downstream processes including membrane (0.2, 0.1 ?m) filters, TFF systems and chromatography columns. •Clarification of bacteria and yeast cell lysates •Endotoxin and nucleic acid removal •Clarification of colloidal and haze forming contaminants. Features and Benefits •Clarification of mammalian cell culture process fluids (cell separation) •Increased throughput with better turbidimetric efficiency •Lower processing costs •Smaller filter assemblies •Consolidation of multiple filter stages •Enhanced protection of downstream membrane filters Cartridge Construction Individual cells of Zeta Plus EXT ZA media are assembled together with polypropylene separators under predetermined compression and unitised by three, 316 stainless steel bands. Each cell is constructed using polypropylene molded edge seals and separators for high performance. Feasibility and Sizing Trials Zeta Plus EXT ZA Series is available in an autoclavable and fully disposable Zeta Plus BCE03 capsules. With 1000 cm? of filtration area, the ready to use Zeta Plus BC filter capsule is ideal for feasibility and sizing trials. Pilot Scale and Small Volume The Zeta Plus BCE03 capsule is one of the options. Small scale pilot runs are recommended to confirm grade selection prior to scale up. Superior Performance Zeta Plus EXT ZA Series filters offer unique advantages in contaminant removal because of their strong electrokinetic properties. In addition to the mechanical exclusion of particles by its depth loading feature, the filter medium adsorbs contaminants too small for removal by mechanical straining. Because most particles in suspension are negatively charged, virtually all contaminants can be removed with proper grade selection. Zeta Plus EXT ZA filters out perform competitive product in each scenario providing both superior through put and turbidimetric efficiency. To the end user, this superior performance translates into lower processing costs, smaller filter assemblies and enhanced protection of downstream membrane filters. Specifications •Effective Cartridge Surface Area:                                        1.1 ft2 (1000 cm2) •Operating Parameters:    •Maximum Operating Pressure:        •Inlet pressure:                                                                      5.5 bar (80 psi) at 25 °C                                                                                                          2.75 bar (40 psi) at 60 °C       •Media pressure (maximum capsule pressure drop): 2.4 bar (35 psi)    •Maximum Operating Temperature:                                    60°C    •Recommended Flush (Pre-use Rinse):                            5.0 l/ft? at 2 lpm/ft? (54 l/m? at 20 litre per min/m?)    •Sterilization Parameters:                                                      Autoclave for 30 minutes at 121°C (up              to 3 cycles)    •Recommended Flow Rates*                                                0.025 - 0.25 gpm (0.1-1.0 lpm) •Nominal Retention Ratings:                                                   0.1 - 2 µm *Lower flow range recommended for maximum throughput Filter Flow Rate Optimum flow rates vary by application, but, in general the flow rate per unit area (flux) should not exceed 10 litre per min/m? of filter medium for best performance. Lower flux rates often result in longer service life, greater throughputs and superior system economics. Sanitary Housings 3M Purification provides a wide array of standard and specially designed sanitary filter housings to accommodate Zeta Plus EXT ZA Series filter cartridges. All housings are designed with the pharmaceutical and bioprocessing industries in mind and feature 316L polished surfaces and easy-to-clean components, along with accessories such as CIP spray-balls and the innovative Zeta Plus Cartridge Lifting Device. Custom design skid systems incorporating Zeta Plus and membrane cartridge filter housings, together with process piping, flow control and complete validation documentation (IQ, OQ), are also available. Zeta Plus EXT ZA cartridges can be retrofitted into 3M Purification’s existing standard Zeta Plus housing offering. To accommodate both 1- and 2- cell 16” diameter Zeta Plus EXT ZA cartridges, 3M Purification has specially designed two sanitary short dome housings that minimise working and hold-up volumes. An ASME code certified housing is available as well as a light-weight band-clamp version. The 8-cell cartridges can be retrofitted into 3M Purifi cation’s existing standard Zeta Plus housing offering. If you need more than one, please let me know.  Please leave me a note if you need more information and pictures.  Thanks. Item No. DL0165

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