Millipore Biopak Filter Milli-q Cdufbi001

US $99.00

  • El Cajon, California, United States
  • Jan 30th
New these filter cost $240.00 Brand new BioPAK filter(s) from Millipore. All components are brand new, the filter bag is factory sealed. I do have multiple filters. The BioPak unit is a disposable ultra-filtration cartridge designed for installation at the outlet of Type 1 water purification systems such as the Milli-Q, Direct-Q, Simplicity or Synergy systems, to produce pyrogen- and nuclease-free ultrapure water for a period of up to three months. The cartridge is composed of polysulfone hollow fibers in a white ABS housing. The BioPak ultrafiltration membrane is designed to optimize the rejection of pyrogens, nucleases and bacteria, while maintaining a high flow rate and minimizing the release of ionic and organic materials. BioPak for pyrogen removal The most common pyrogens are endotoxins, i.e., lipopolysaccharides (LPS) from the walls of Gram negative bacteria. The LPS have two major parts: a hydrophilic polysaccharide chain with antigenic regions and a hydrophobic lipid group. As the polysaccharide chain is variable in length, the LPS molecular weight ranges from 3,000 to 25,000 Dalton. In ultrapure water, the LPS sub-units aggregate to form higher molecular weight structures that can be removed by ultrafiltration membranes with cut off below 20,000 Dalton. Pyrogens are known to affect cell culture and biochemistry experiments in numerous ways. It has been demonstrated that their interaction with cell membranes causes morphological changes and damage, as well as the secretion of specific substances such as tumor necrosis factor, cytokines or enzymes. Pyrogens also affect the cell division process (enhancing or reducing it) depending on the nature of the cell line. The presence of pyrogens also may affect analytical techniques such as electrophoresis. For these reasons, it is good laboratory practice to remove pyrogens from all solutions used in cell culture and other biochemical applications. Experiments performed in Millipore R&D laboratories have demonstrated that the BioPak ultrafiltration cartridge can be used for at least 90 days to treat Milli-Q ultrapure water and obtain product water with a pyrogen level below 0.001 EU/mL. BioPak for Nuclease removal Challenge tests performed in Millipore R&D laboratories have demonstrated that the BioPak cartridge allows easy production of ultrapure water that is both RNase-free (< 0.01 ng/mL) and DNase-free (< 4 pg/?L). Previous experiments also have shown that ultrafiltration with a properly validated device is just as efficient as diethylpyrocarbonate (DEPC) for RNase removal from ultrapure water without the negative aspects of DEPC treatment: lengthy treatment time and contamination of the treated water by CO2 and ethanol.  
Condition:
New: A brand-new, unused, unopened, undamaged item in its original packaging (where packaging is applicable). Packaging should be the same as what is found in a retail store, unless the item is handmade or was packaged by the manufacturer in non-retail packaging, such as an unprinted box or plastic bag. See the seller's listing for full details. ...
Brand Millipore
MPN BioPAK
Model CDUFBI001
Country/Region of Manufacture United States

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